In 2004, I joined the Chengdu Institute of Biology, Chinese Academy of Sciences as a researcher, received my Ph.D. degree from the Department of Chemistry of Sichuan University in 2000. From 1999 to 2004, I worked as a PhD and postdoctoral fellow at the University of Hong Kong for 5 years, and from 2010 to 2011, I was an advanced visiting scholar of small molecule applications in the treatment and diagnosis of tumors and neurological diseases at Washington University in St. Louis, USA. In recent years, I has been mainly engaged in the research and development of original natural medicines and functional health products with independent intellectual property rights, and has carried out systematic research on the basic theories and key technologies closely related to the research and development process of new drugs and functional health products, including the separation and identification of natural products, structural transformation, screening of active small molecule compounds, structure-activity relationship and molecular target research, as well as research on new processes and methods of drug synthesis.

1. Design, Synthesis, and Anti-inflammatory Activity Characterization of Novel Brain-permeable HDAC6 Inhibitors，Eur. J. Med. Chem., 2023, 254, 115327-115335 

2. Design, Synthesis and Structure–activity Relationship Studies on Erianin Analogues as Pyruvate Carboxylase Inhibitors in Hepatocellular Carcinoma Cells, Org. Biomol. Chem., 2023, 21, 7005-7017.

3. Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP–Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis，J. Med. Chem., 2022, 65(16), 11010-11033.

4. Design, synthesis, and Insecticidal Activity of Novel Doramectin Derivatives containing Acylurea and Acylthiourea based on Hydrogen Bonding. J. Agric. Food. Chem. 2020. 5806-5815.

5. Development of Chalcone-O-alkylamine Derivatives as Multifunctional Agents Against Alzheimer's Disease, Eur. J. Med. Chem., 2019, 183, 111737-111752.

1. Discovery, Evaluation and Transformation of Active Natural Compounds, Biological Resources Program (KFJ-BRP-008), Chinese Academy of Sciences, 2019.10–2024.10

2. Research on the Quality Evaluation of Sichuan Authentic Medicinal Materials (Fritillaria) and Its Pesticide Residue Detection Methods Based on Quality Markers, Key Laboratory of Quality Testing and Evaluation of Chinese Materia Medica, National Medical Products Administration, 2023.6-2024.6.

3. Quality study on a series of microbial manufacturing APIs and related substances, Chongqing Daxin Pharmaceutical Co., Ltd., 2021, 01-2024.12.

4. Research and Development of Green Antistress Agents and Highly Active Insecticides, Technology Service Network Initiative (No. KFJ-SW-STS-143-1), Chinese Academy of Sciences, 2016.1-2019.12

5. Design and Synthesis of Chemical Small Molecules Based on Sigma-1 Receptor Signaling Pathway and Their Anticancer Activity, National Natural Science Foundation of China, 2013.1-2016.12

6. Research and Application of New Technology for Green Asymmetric Synthesis of Chiral α-Amino Acids and Their Derivatives, "West Light" talent Scholarship Program and Chinese Academy of Sciences, 2013.1–2015.12

7. Study on the structure and structure-activity relationship of low molecular weight polygonatum oligosaccharides with antiviral activity, National Natural Science Foundation of China, 2009.1-2011.12

8. Research on the extraction of gingerol by supercritical extraction combined with molecular distillation technology, "West Light" talent Program, 2006.1–2008.12.