The plants of the genus Lagochilus are distributed in Iran, Afghanistan, Mongolia, Russia, and China. There globally are 30 species in the genus and most of them are grown in Inner Mongolia, Ningxia, Gansu, Shaanxi, and Xinjiang of China. Some plants of the genus Lagochilus were applied for the treatment of allergic dermatosis and for styptic.

Previous chemical studies on the plants of the genus Lagochilus led to the isolation of diterpenoids, flavonoids, coumarins, iridoid glycosides, and polysaccharides . Lagoden, a drug based on a diterpenoid lactone isolated from plants of the genus Lagochilus, is widely used as an effective hemostatic

Phytochemical investigations on the 95% ethanolic extract of the aerial parts of Lagochilus ilicifolius offered 7 iridoid glucosides, 2 aliphatic alcohols, 1 diterpene, and 1 phenylpropanoid. Their structures were identified to be 8-O-acetylharpagide (1), ajugoside (2), ajujol (3), harpagide (4), geniposidic acid (5), mussaenosidic acid (6), 8-deoxyshanzhiside (7), citrusin C (8), phytol (9), 12-hentriacontanol (10), and octacosanol (11) on the basis of spectroscopic data interpretation and chemical comparison. Compounds 2~3 and 5~11 were isolated from the genus Lagochilus for the first time.