A new ent-labdane diterpenoid, 19-O-beta-D-glucopyranosyl-ent-labda-8(17),13-dien-15,16,19-triol, together with six known ent-labdane diterpenoids, was isolated from the aerial parts of Andrographis paniculata. The structure of the new compound was elucidated by extensive spectral analysis. CIB Prof.DING Lisheng's team made this research.

Andrographis paniculata Nees. (Acanthaceae) is a traditional medicinal plant growing in China and India. The extract of A. paniculata and its major ent-labdane diterpenoids have been to shown to display antiviral, bacteriostatic, immunostimulatory, anthelmintic, hepaprotective and immunostimulating activities and In the continuing investigation on bioactive natural products from the well-known herb, researchers isolated and identified a new ent-labdane diterpenoid, together with six known ones from the 85%-MeOH crude extract of the aerial part of A. paniculata, which were purchased from Guangxi Province in October 2008. In this study, the structure elucidation of the new compound 1 is presented.

More results have  been published online in CHINESE CHEMICAL LETTERS 2010, 21 ( 9 ): 1091-1093.